c-Fos importance for brain development
نویسندگان
چکیده
منابع مشابه
c-Fos importance for brain development
an immediate early response gene involved in cell proliferation and differentiation after extracellular stimuli, whereas its deregulation has been associated to oncogenic progression. As other members of the FOS family proteins (Fra-1, Fra-2, FosB) and proteins of the ATF family, c-Fos can heterodimerize with members of the JUN family (c-Jun, JunB, JunD) to form the transcription factor activat...
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c-Fos is a proto-oncogene involved in diverse cellular functions. Its deregulation has been associated to abnormal development and oncogenic progression. c-fos-/- mice are viable but present a reduction in their body weight and brain size. We examined the importance of c-Fos during neocortex development at 13.5, 14.5 and 16.5 days of gestation. At E14.5, neocortex thickness, apoptosis, mitosis ...
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Taste neophobia refers to a reduction in consumption of a novel taste relative to when it is familiar. To gain more understanding of the neural basis of this phenomenon, the current study examined whether a novel taste (0.5% saccharin) supports a different pattern of c-Fos expression than the same taste when it is familiar. Results revealed that the taste of the novel saccharin solution evoked ...
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ژورنال
عنوان ژورنال: Aging
سال: 2015
ISSN: 1945-4589
DOI: 10.18632/aging.100862